Sustained suppression of hepatitis C virus by high doses of interferon and ribavirin in adult hemophilic patients.

@article{Santagostino2004SustainedSO,
  title={Sustained suppression of hepatitis C virus by high doses of interferon and ribavirin in adult hemophilic patients.},
  author={Elena Santagostino and Francesca De Filippi and M G Rumi and Monica Rivi and Massimo Colombo and Pier Mannuccio Mannucci},
  journal={Transfusion},
  year={2004},
  volume={44 5},
  pages={790-4}
}
BACKGROUND In a recent randomized controlled study, only a minority (15%) of adult hemophiliacs with chronic HCV achieved a sustained virologic response to treatment with interferon (IFN) and ribavirin given at standard doses. STUDY DESIGN AND METHODS Whether the therapeutic response might be improved in these patients by increasing the doses of IFN was evaluated. Thirty-four previously untreated, adult hemophiliacs with chronic HCV but negative for HIV were investigated. There were 33 men… CONTINUE READING