Sustained renal interstitial macrophage infiltration following chronic angiotensin II infusions.

@article{Ozawa2007SustainedRI,
  title={Sustained renal interstitial macrophage infiltration following chronic angiotensin II infusions.},
  author={Yuri Ozawa and Hiroyuki Kobori and Yuki Suzaki and Luis Gabriel Navar},
  journal={American journal of physiology. Renal physiology},
  year={2007},
  volume={292 1},
  pages={
          F330-9
        }
}
Chronic angiotensin (ANG) II infusions into rats lead to augmented intrarenal levels of ANG II and inflammatory factors, impaired renal function, and progressive hypertension. Residual effects persist after cessation of ANG II infusions, as manifested by a hypertensive response to high-salt intake. This study was performed to determine the residual cytokines and chemokines following the cessation of ANG II infusion. Male Sprague-Dawley rats, maintained on a normal diet, received either a sham… CONTINUE READING

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