Sustained release of collagen VI potentiates sciatic nerve regeneration by modulating macrophage phenotype.

@article{Lv2017SustainedRO,
  title={Sustained release of collagen VI potentiates sciatic nerve regeneration by modulating macrophage phenotype.},
  author={D. G. Lv and Lijuan Zhou and Xianyu Zheng and Yongcheng Hu},
  journal={The European journal of neuroscience},
  year={2017},
  volume={45 10},
  pages={1258-1267}
}
Although the peripheral nervous system has an intrinsic ability for repair and regeneration after injury, bridging long peripheral nerve defects remains a challenge. Functional nerve regeneration depends on interactions among axons, Schwann cells, fibroblasts and immune cells. Macrophages, as immune cells recruited early in this process, show polarization… CONTINUE READING