Sustained phosphorylation of MARCKS in differentiating neurogenic regions during chick embryo development.

@article{Zolessi2001SustainedPO,
  title={Sustained phosphorylation of MARCKS in differentiating neurogenic regions during chick embryo development.},
  author={Flavio R Zolessi and Cristina Arruti},
  journal={Brain research. Developmental brain research},
  year={2001},
  volume={130 2},
  pages={257-67}
}
MARCKS, a substrate for several kinases, has critical functions in morphogenetic processes involved in the development of the nervous system. We previously described the purification of MARCKS from chick embryo brain, using a monoclonal antibody (mAb 3C3), raised against embryonic neural retina. Here we show that mAb 3C3 is an antibody sensitive to phosphorylation state. We used it to explore the appearance and developmental progression of phospho-MARCKS (ph-MARCKS) during initial stages of… CONTINUE READING