Sustained hyperphagia in adolescent rats that experienced neonatal maternal separation

@article{Ryu2008SustainedHI,
  title={Sustained hyperphagia in adolescent rats that experienced neonatal maternal separation},
  author={Vitaly Ryu and Jae Hyeok Lee and Sang Yoo and Xue Feng Gu and Young Wha Moon and Jeong Won Jahng},
  journal={International Journal of Obesity},
  year={2008},
  volume={32},
  pages={1355-1362}
}
Objective:To examine the neurobiological basis of bingeing-related eating disorders using an animal model system.Design:Sprague–Dawley pups were separated from dam for 3 h daily during the first two weeks of birth (maternal separation (MS)), or left undisturbed (non-handled (NH)). Pups were subjected to repeated fasting/refeeding (RF) cycles; that is, 24 h food deprivation and 24 h RF (NH/RF or MS/RF), or had free access to food and water (NH/fed control (FC) or MS/FC) from postnatal day (PND… CONTINUE READING
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