Sustained elevation in circulating catecholamine levels during polymicrobial sepsis.

@article{Hahn1995SustainedEI,
  title={Sustained elevation in circulating catecholamine levels during polymicrobial sepsis.},
  author={P Y Hahn and Ping Wang and Saskia Tait and Zheng F. Ba and S Scott Reich and Irshad H. Chaudry},
  journal={Shock},
  year={1995},
  volume={4 4},
  pages={269-73}
}
Although studies have indicated that the levels of catecholamines increase during sepsis, it remains unknown whether the elevated levels of epinephrine, norepinephrine, and dopamine observed in early sepsis are sustained during late, hypodynamic stages of sepsis. In this study, rats were subjected to sepsis by cecal ligation and puncture (CLP, i.e., polymicrobial sepsis). Immediately after CLP or sham operation, animals received 3 mL/100 g body weight normal saline subcutaneously. At .5, 2, 10… CONTINUE READING

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