Sustained efficacy and safety of a 300IR daily dose of a sublingual solution of birch pollen allergen extract in adults with allergic rhinoconjunctivitis: results of a double-blind, placebo-controlled study

@inproceedings{Worm2014SustainedEA,
  title={Sustained efficacy and safety of a 300IR daily dose of a sublingual solution of birch pollen allergen extract in adults with allergic rhinoconjunctivitis: results of a double-blind, placebo-controlled study},
  author={M. A. J. Arne Worm and Sabina Rak and Fr{\'e}d{\'e}ric de Blay and H J Malling and Michel M{\'e}lac and V{\'e}ronique Cadic and Robert K. Zeldin},
  booktitle={Clinical and translational allergy},
  year={2014}
}
BACKGROUND Allergic rhinoconjunctivitis (ARC) due to birch pollen is a growing health concern in Europe. Here, we report the efficacy and safety of 300IR birch pollen sublingual solution administered discontinuously for 2 consecutive years to patients with birch-associated allergic rhinoconjunctivitis. METHODS Birch pollen-allergic adults were randomized in this double blind study to 300IR birch pollen sublingual solution or placebo, daily, starting 4 months before and continuing through the… CONTINUE READING
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J Bousquet, N Khaltaev, +7 authors C VanWeel
J Allergy Clin Immunol • 2010

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