Sustained effectiveness of converting-enzyme inhibition in patients with severe congestive heart failure.

@article{Dzau1980SustainedEO,
  title={Sustained effectiveness of converting-enzyme inhibition in patients with severe congestive heart failure.},
  author={Victor J. Dzau and Wilson Steven Colucci and Gordon H. Williams and Gregory D. Curfman and Leonard G. Meggs and Norman Kenneth Hollenberg},
  journal={The New England journal of medicine},
  year={1980},
  volume={302 25},
  pages={1373-9}
}
Eight patients with severe congestive heart failure refractory to conventional therapy, including vasodilators, were given captopril (seven patients) or teprotide (one patient). All had dyspnea, edema, elevated pulmonary wedge pressure (28.0 +/- 2.6 mm Hg), low cardiac index (1.6 +/- 0.1 liters per minute per square meter), and elevated levels of serum creatinine (2.3 +/- 0.2 mg per deciliter [203.3 +/- 17.7 mumol per liter]), blood urea nitrogen (48 +/- 5 mg per deciliter [17.1 +/- 1.8 mmol of… CONTINUE READING

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