Sustained delivery of captopril from floating matrix tablets.


The development of a controlled release formulation of captopril has been a challenge for some time. In this work, the in vitro sustained release of captopril from Metolose SH 4000 SR/sodium bicarbonate floating tablets has been studied, varying the proportions of Metolose and bicarbonate. This was studied at two different compaction pressures. Other… (More)
DOI: 10.1016/j.ijpharm.2008.05.040


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@article{JimnezMartnez2008SustainedDO, title={Sustained delivery of captopril from floating matrix tablets.}, author={In{\'e}z Jim{\'e}nez-Mart{\'i}nez and Tom{\'a}s Quirino-Barreda and Leopoldo Villafuerte-Robles}, journal={International journal of pharmaceutics}, year={2008}, volume={362 1-2}, pages={37-43} }