Sustained cutaneous vasoconstriction during and following cyrotherapy treatment: Role of oxidative stress and Rho kinase.

@article{Christmas2016SustainedCV,
  title={Sustained cutaneous vasoconstriction during and following cyrotherapy treatment: Role of oxidative stress and Rho kinase.},
  author={Kevin M. Christmas and Jordan C Patik and Sepideh Khoshnevis and Kenneth R. Diller and R Matthew Brothers},
  journal={Microvascular research},
  year={2016},
  volume={106},
  pages={96-100}
}
Cryotherapy is a therapeutic technique using ice or cold water applied to the skin to reduce bleeding, inflammation, pain, and swelling following soft tissue trauma and injury. While beneficial, there are some side effects such as pronounced vasoconstriction and tissue ischemia that are sustained for hours post-treatment. This study tested the hypothesis that this vasoconstriction is mediated by 1) the Rho-kinase pathway and/or 2) elevated oxidative stress. 9 subjects were fitted with a… CONTINUE READING