Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

@inproceedings{Sun2011SustainedAR,
  title={Sustained axon regeneration induced by co-deletion of PTEN and SOCS3},
  author={Fang Sun and Kevin Kiwon Park and St{\'e}phane Belin and Dongqing Wang and Tao Lu and Gang Chen and Kang Zhang and Cecil Yeung and Guoping Feng and Bruce A. Yankner and Zhigang He},
  booktitle={Nature},
  year={2011}
}
A formidable challenge in neural repair in the adult central nervous system (CNS) is the long distances that regenerating axons often need to travel in order to reconnect with their targets. Thus, a sustained capacity for axon regeneration is critical for achieving functional restoration. Although deletion of either phosphatase and tensin homologue (PTEN), a negative regulator of mammalian target of rapamycin (mTOR), or suppressor of cytokine signalling 3 (SOCS3), a negative regulator of Janus… CONTINUE READING

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