Sustained Complete Response to Metronomic Chemotherapy in a Child with Refractory Atypical Teratoid Rhabdoid Tumor: A Case Report

@inproceedings{Berland2017SustainedCR,
  title={Sustained Complete Response to Metronomic Chemotherapy in a Child with Refractory Atypical Teratoid Rhabdoid Tumor: A Case Report},
  author={Mahe Berland and Laetitia Padovani and Ang{\'e}lique Rome and G Pech-gourg and Dominique F. Figarella-Branger and Nicolas Andr{\'e}},
  booktitle={Front. Pharmacol.},
  year={2017}
}
Atypical teratoid rhabdoid tumor (ATRT) is a rare and highly aggressive embryonal tumor of the central nervous system with a dismal prognosis and no definitive guidelines for treatment, especially at relapse or in case of refractory disease. Metronomic chemotherapy (MC) has emerged as a new treatment option in solid malignancies, with lower toxicity and is frequently combined with drug repositioning. We report a case of ATRT in an 8-year-old boy who progressed during multimodal therapy… CONTINUE READING
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