Sustainable Flow Synthesis of Encoded Beads for Combinatorial Chemistry and Chemical Biology.

  title={Sustainable Flow Synthesis of Encoded Beads for Combinatorial Chemistry and Chemical Biology.},
  author={Hongxia Hu and Sergei Nikitin and Adam Bj{\o}rnholdt Berthelsen and Frederik Diness and Sanne Schoffelen and Morten Meldal},
  journal={ACS combinatorial science},
  volume={20 8},
Monosized beads of polar resins were synthesized for combinatorial chemistry and chemical biology by sustainable microchannel flow synthesis. Regular, biocompatible, and optically encoded beads could be efficiently prepared on large scale and in high yield. In a preparative flow polymerization instrument, taking advantage of a designed T-connector for droplet formation, quality beads were synthesized with accurate size control using a minimal amount of recirculating silicon oil as suspension… 

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