Suspended animation-like state protects mice from lethal hypoxia.

  title={Suspended animation-like state protects mice from lethal hypoxia.},
  author={Eric A Blackstone and Mark B Roth},
  volume={27 4},
Joseph Priestley observed the high burn rate of candles in pure oxygen and wondered if people would "live out too fast" if we were in the same environment. We hypothesize that sulfide, a natural reducer of oxygen that is made in many cell types, acts as a buffer to prevent unrestricted oxygen consumption. To test this, we administered sulfide in the form of hydrogen sulfide (H2S) to mice (Mus musculus). As we have previously shown, H2S decreases the metabolic rate of mice by approximately 90… CONTINUE READING