Suspected black cohosh hepatotoxicity: no evidence by meta-analysis of randomized controlled clinical trials for isopropanolic black cohosh extract

@article{Naser2011SuspectedBC,
  title={Suspected black cohosh hepatotoxicity: no evidence by meta-analysis of randomized controlled clinical trials for isopropanolic black cohosh extract},
  author={B Naser and J{\"o}rg Schnitker and M J Minkin and Susana Garcia de Arriba and K. U. Nolte and R{\"u}diger Osmers},
  journal={Menopause},
  year={2011},
  volume={18},
  pages={366-375}
}
Objective: Black cohosh, a popular herbal treatment for menopausal symptoms, has been implicated in a number of hepatotoxicity case reports. The purpose of this investigation was to analyze data gained from clinical trials on the effect of black cohosh on liver function. Methods: A meta-analysis of randomized, double-blind, and controlled clinical trials was conducted. These studies primarily evaluated the efficacy and safety of the isopropanolic black cohosh extract (iCR) in perimenopausal and… 
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