Susceptible and protective eNOS haplotypes in hypertensive black and white subjects.

@article{Sandrim2006SusceptibleAP,
  title={Susceptible and protective eNOS haplotypes in hypertensive black and white subjects.},
  author={Valeria Cristina Sandrim and Eduardo B Coelho and Fernando Nobre and Gustavo Marin Arado and Vera Lucia Lanchote and Jos{\'e} Eduardo Tanus-Santos},
  journal={Atherosclerosis},
  year={2006},
  volume={186 2},
  pages={
          428-32
        }
}
Polymorphisms in the endothelial nitric oxide synthase (eNOS) gene have been inconsistently associated with hypertension. This inconsistency may derive from population stratification secondary to ethnic diversity, and consideration limited to only one rather than combinations of polymorphisms. We studied three genetic variations in the eNOS gene: a single nucleotide polymorphism in the promoter region (T-786C), in exon 7 (Glu298Asp), and a variable number of tandem repeats in intron 4 (b/a) of… CONTINUE READING
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