Susceptibility to sarcomere injury induced by single stretches of maximally activated muscles of mdx mice.

@article{Consolino2004SusceptibilityTS,
  title={Susceptibility to sarcomere injury induced by single stretches of maximally activated muscles of mdx mice.},
  author={Christina Marie Consolino and Susan V. Brooks},
  journal={Journal of applied physiology},
  year={2004},
  volume={96 2},
  pages={
          633-8
        }
}
The purpose was to investigate the contribution of mechanical damage to sarcomeres to the greater susceptibility of dystrophic muscle fibers to contraction-induced injury. Single stretches provide an effective method for studying mechanical factors that contribute to the initiation of contraction-induced injury. We hypothesized that, after single stretches, the deficits in isometric force would be greater for muscles of mdx than C57BL/10 mice, whereas membrane damage would be minimal for all… CONTINUE READING

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