Susceptibility of the cerebellum to thiamine deficiency

@article{Mulholland2006SusceptibilityOT,
  title={Susceptibility of the cerebellum to thiamine deficiency},
  author={Patrick J. Mulholland},
  journal={The Cerebellum},
  year={2006},
  volume={5},
  pages={55-63}
}
Thiamine or vitamin B1, an essential nutrient absorbed from the diet, is involved in vital brain metabolic and cellular functions, including carbohydrate metabolism and neurotransmitter production. Diencephalic regions and, in particular, the cerebellum demonstrate lesions in cases of prolonged thiamine deficiency, such as that observed in alcohol-dependent individuals or in patients with cancer or AIDS. The purpose of this review is to demonstrate recent evidence of cerebellar dysfunction… CONTINUE READING
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