Susceptibility of immunodeficient gene-knockout mice to urinary tract infection.

@article{JonesCarson1999SusceptibilityOI,
  title={Susceptibility of immunodeficient gene-knockout mice to urinary tract infection.},
  author={Jessica Jones-Carson and Edward J Balish and David T. Uehling},
  journal={The Journal of urology},
  year={1999},
  volume={161 1},
  pages={338-41}
}
PURPOSE Clinical and experimental evidence indicates that mucosal immunity to urinary tract infection involves B and T-cell functions. The present study was conducted to assess the susceptibility of immunocompetent and immunodeficient mice with genetically engineered deletions in T and B-cell functions to experimentally induced urinary tract infections (UTI) with Escherichia coli. MATERIALS AND METHODS Interferon-gamma (IFN-gamma), interleukin-4 (IL-4), IL-10, inducible nitric oxide synthase… CONTINUE READING