Susceptibility of hematopoietic stem cells to pathogens: role in virus/bacteria tropism and pathogenesis.

@article{KolbMurer2003SusceptibilityOH,
  title={Susceptibility of hematopoietic stem cells to pathogens: role in virus/bacteria tropism and pathogenesis.},
  author={Annette Kolb-M{\"a}urer and W. Goebel},
  journal={FEMS microbiology letters},
  year={2003},
  volume={226 2},
  pages={
          203-7
        }
}
Human hematopoietic stem cells (HSCs) are generated in the bone marrow and differentiate into erythrocytes, granulocytes, monocytes, megacaryocytes, and lymphocytes. HSCs may be manipulated under different conditions. Advances in cell biology result in a better understanding of the relationship between viruses/bacteria and hematopoietic cells. Microbial infections can lead to profound disturbance of hematopoiesis. Infection may augment the production of cytokines, with proliferation and… CONTINUE READING

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