Susceptibility of cells in different stages of the mitotic cycle to transformation by polyoma virus.


The susceptibility to malignant transformation by polyoma virus of cells infected in different phases of the mitotic cycle has been studied using the hamster fibroblast line BHK21 (clone 13). It appears that cell competence is not restricted to a portion of the mitotic cycle. However, susceptibility to transformation increases with the progress of the cell… (More)


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