Susceptibility of Campylobacter jejuni to organic acids and monoacylglycerols

@article{Molatov2010SusceptibilityOC,
  title={Susceptibility of Campylobacter jejuni to organic acids and monoacylglycerols},
  author={Zuzana Molatov{\'a} and Eva Skřivanov{\'a} and B. Mac{\'i}as and Neil Ross McEwan and Pavel Březina and Milan Marounek},
  journal={Folia Microbiologica},
  year={2010},
  volume={55},
  pages={215-220}
}
Organic acids can be used as feed supplements or for treatment of poultry carcasses in processing plants. The antimicrobial activity of nineteen organic acids and two monoacylglycerols in cultures of Campylobacter jejuni CCM 6214T (ATCC 33560) was determined using a SYBR Green-based real-time PCR assay. The IC50 was a concentration at which only 50 % of a bacteria specific DNA sequence was amplified. Caprylic, capric and lauric acids were the most efficient antimicrobials among the compounds… 
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References

SHOWING 1-10 OF 23 REFERENCES
Inhibition of Campylobacter jejuni in chicken by ethanol, hydrogen peroxide, and organic acids
Growth inhibition of Campylobacter jejuni ATCC 33291 was observed in the presence of various preservatives at various temperatures. The addition of ethanol (0.5% to 5%), hydrogen peroxide (0.05%),
Short-chain fatty acids and l-lactate as feed additives to control Campylobacter jejuni infections in broilers
TLDR
In conclusion, butyrate-coated micro-beads do not protect broilers from caecal colonization with C. jejuni in vitro, and one acid was retained for use as a feed additive in an in vivo trial.
In vitro study on the effect of organic acids on Campylobacter jejuni/coli populations in mixtures of water and feed.
TLDR
It can be concluded that organic acids, individually or in combination, have a strong bactericidal effect on Campylobacter spp.
Bacteriocins reduce Campylobacter colonization and alter gut morphology in turkey poults.
TLDR
The dynamic reduction in crypt depth and goblet cell density in turkeys dosed with bacteriocin may provide clues to how bacteriOCins inhibit enteric Campylobacter.
Use of oleic acid to reduce the population of the bacterial flora of poultry skin.
TLDR
Findings indicate that oleic acid reduces the number of bacteria on the skin of processed broilers and that the fatty acid is bactericidal to several spoilage and pathogenic bacteria associated with poultry.
The natural feed additive caprylic acid decreases Campylobacter jejuni colonization in market-aged broiler chickens.
TLDR
It is suggested that therapeutic supplementation of caprylic acid in the feed can effectively decrease Campylobacter in market-aged chickens and may be a potential treatment for decreasing pathogen carriage in poultry.
Detection of Campylobacter jejuni in dairy farm environmental samples using SYBR Green real-time polymerase chain reaction.
TLDR
The results indicate that the SYBR Green real-time PCR assay provides a specific, reproducible, and simple method for detecting C. jejuni in dairy farm environmental samples.
Perspectives on the use of organic acids and short chain fatty acids as antimicrobials.
  • S. Ricke
  • Biology, Medicine
    Poultry science
  • 2003
TLDR
Development and application of molecular tools to study pathogen behavior in preharvest and postharvest food production environments will enable dissection of specific bacterial genetic regulation involved in response to organic acids, which could lead to the development of more targeted strategies to control foodborne pathogens with organic acids.
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