Susceptibility of B-cell deficient C57BL/6 (microMT) mice to Neospora caninum infection.

@article{Eperon1999SusceptibilityOB,
  title={Susceptibility of B-cell deficient C57BL/6 (microMT) mice to Neospora caninum infection.},
  author={S Eperon and K Br{\"o}nnimann and Andrew Hemphill and Bruno Gottstein},
  journal={Parasite immunology},
  year={1999},
  volume={21 5},
  pages={
          225-36
        }
}
Neospora caninum is a coccidian parasite of veterinary importance by causing abortion or stillbirth in cattle among other problems in diverse animal species. We assessed an experimental murine model for its suitability to study the immune response to N. caninum infection. Thus, wild-type (wt) C57BL/6 mice and B-cell (and consequently antibody)-deficient microMT mice were infected with N. caninum tachyzoites and sacrificed at days 10, 24 and 29-44 post infection (dpi). Various organs were… CONTINUE READING
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