Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study.

@article{Assimes2008SusceptibilityLF,
  title={Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study.},
  author={Themistocles L. Assimes and Joshua W. Knowles and Analabha Basu and Carlos Iribarren and Audrey Southwick and Hua Tang and Devin M Absher and Jun Li and Joan M. Fair and Geoffrey D. Rubin and Stephen Sidney and Stephen P. Fortmann and Alan S. Go and Mark A. Hlatky and Richard M. Myers and Neil J. Risch and Thomas Quertermous},
  journal={Human molecular genetics},
  year={2008},
  volume={17 15},
  pages={2320-8}
}
A susceptibility locus for coronary artery disease (CAD) at chromosome 9p21 has recently been reported, which may influence the age of onset of CAD. We sought to replicate these findings among white subjects and to examine whether these results are consistent with other racial/ethnic groups by genotyping three single nucleotide polymorphisms (SNPs) in the risk interval in the Atherosclerotic Disease, Vascular Function, and Genetic Epidemiology (ADVANCE) study. One or more of these SNPs was… CONTINUE READING