Susceptibility for ischemic stroke in Korean population is associated with polymorphisms of the Fc gamma receptor IIA.

@article{Kim2009SusceptibilityFI,
  title={Susceptibility for ischemic stroke in Korean population is associated with polymorphisms of the Fc gamma receptor IIA.},
  author={Yangseok Kim and Jin-Ho Yoo and Byung-Cheol Lee},
  journal={Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis},
  year={2009},
  volume={20 5},
  pages={353-7}
}
Fc gamma receptor IIA could influence atherogenic processes through the production of superoxide anions, cytokines, and proteolytic enzymes as well as by oxidation of lipoproteins and enhancement of foam cell formation. In this study, we performed an interaction analysis between FCGR2A polymorphisms and ischemic stroke using direct DNA sequencing after the selection of Fc gamma receptor IIA gene based on genome-wide association study. Four of the FCGR2A polymorphisms, rs7511868 [odds ratio (OR… CONTINUE READING