Susceptibilities of periodontopathogenic and cariogenic bacteria to antibacterial peptides, {beta}-defensins and LL37, produced by human epithelial cells.

@article{Ouhara2005SusceptibilitiesOP,
  title={Susceptibilities of periodontopathogenic and cariogenic bacteria to antibacterial peptides, \{beta\}-defensins and LL37, produced by human epithelial cells.},
  author={K Ouhara and Hitoshi Komatsuzawa and Sakuo Yamada and Hideki Shiba and Tamaki Fujiwara and Masaru Ohara and Koji Sayama and Koji Hashimoto and Hidemi Kurihara and Motoyuki Sugai},
  journal={The Journal of antimicrobial chemotherapy},
  year={2005},
  volume={55 6},
  pages={888-96}
}
OBJECTIVES Antimicrobial peptides are one of the factors involved in innate immunity. The susceptibility of periodontopathogenic and cariogenic bacteria to the major antimicrobial peptides produced by epithelia was investigated. METHODS Synthetic antimicrobial peptides of human beta-defensin-1 (hBD1), hBD2, hBD3 and LL37 (CAP18) were evaluated for their antimicrobial activity against oral bacteria. They included Actinobacillus actinomycetemcomitans (20 strains), Porphyromonas gingivalis (6… CONTINUE READING
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