Susceptibilities of Nonhuman Primates to Chronic Wasting Disease

@inproceedings{Race2009SusceptibilitiesON,
  title={Susceptibilities of Nonhuman Primates to Chronic Wasting Disease},
  author={Brent Race and Kimberly D. Meade-White and Michael A Miller and Kent D. Barbian and Richard L. Rubenstein and Giuseppe Lafauci and Larisa Cerven{\'a}kov{\'a} and Cynthia Favara and Donald Gardner and Dan C. Long and Michael J. Parnell and James F. Striebel and Suzette A. Priola and Anne Marie Ward and Elizabeth S. Williams and Richard W. Race and Bruce Chesebro},
  booktitle={Emerging infectious diseases},
  year={2009}
}
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy, or prion disease, that affects deer, elk, and moose. Human susceptibility to CWD remains unproven despite likely exposure to CWD-infected cervids. We used 2 nonhuman primate species, cynomolgus macaques and squirrel monkeys, as human models for CWD susceptibility. CWD was inoculated into these 2 species by intracerebral and oral routes. After intracerebral inoculation of squirrel monkeys, 7 of 8 CWD isolates induced a… CONTINUE READING

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