Surviving the macrophage: tools and tricks employed by Mycobacterium tuberculosis.

  title={Surviving the macrophage: tools and tricks employed by Mycobacterium tuberculosis.},
  author={Rajesh Jayachandran and Somdeb BoseDasgupta and Jean Pieters},
  journal={Current topics in microbiology and immunology},
Mycobacterium tuberculosis has evolved to withstand one of the most inhospitable cells within the human body, namely the macrophage, a cell that is normally geared toward the destruction of any invading microbe. How M. tuberculosis achieves this is still incompletely understood; however, a number of mechanisms are now known that provide advantages to M. tuberculosis for its survival and proliferation inside the macrophage. While some of these mechanisms are mediated by factors released by M… CONTINUE READING

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