Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock 2012

@article{Dellinger2013SurvivingSC,
  title={Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock 2012},
  author={Richard Phillip Dellinger and Mitchell M. Levy and Andrew Rhodes and Djillali Annane and Herwig Gerlach and Steven M. Opal and Jonathan E. Sevransky and Charles L Sprung and Ivor S. Douglas and Roman Z. Jaeschke and Tiffany Medlin Osborn and Mark E. Nunnally and Sean Robert Townsend and Konrad Reinhart and Ruth Kleinpell and Derek C. Angus and Clifford S. Deutschman and Fl{\'a}via Ribeiro Machado and Gordon David Rubenfeld and Steven A. R. Webb and Richard Beale and Jean Louis Vincent and Rui Moreno},
  journal={Critical Care Medicine},
  year={2013},
  volume={41},
  pages={580–637}
}
Objective:To provide an update to the “Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock,” last published in 2008. Design:A consensus committee of 68 international experts representing 30 international organizations was convened. Nominal groups were assembled at key international meetings (for those committee members attending the conference). A formal conflict of interest policy was developed at the onset of the process and enforced throughout. The entire… Expand

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Source control represents a key component of success in therapy of sepsis and is the best way to reduce quickly the bacterial inoculum, although most recommendations are graded as D or E due to the difficulty to perform appropriate randomized clinical trials. Expand
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
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Evidence-based recommendations can be made regarding many aspects of the acute management of sepsis and septic shock that are hoped to translate into improved outcomes for the critically ill patient. Expand
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A series of recommendations based on the best available evidence to guide clinicians providing nursing care to patients with severe sepsis are provided, with an urgent need for further evidence to better inform this area of critical care. Expand
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The Surviving Sepsis Campaign was associated with sustained, continuous quality improvement in sepsis care and a reduction in reported hospital mortality rates wasassociated with participation. Expand
The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis
TLDR
The Surviving Sepsis Campaign was associated with sustained, continuous quality improvement in sepsis care and a reduction in reported hospital mortality rates wasassociated with participation. Expand
Cost-effectiveness of the Surviving Sepsis Campaign protocol for severe sepsis: a prospective nation-wide study in Spain
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The SSC protocol seems to be a cost-effective option for treating severe sepsis in Spain after the implementation of an educational program compared with the conventional care of severe septicaemia. Expand
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A three-step sepsis screening tool with escalating levels of decision making is developed and implemented and has decreased sepsi-related mortality in the SICU by one third. Expand
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The benefits and risks of corticosteroid treatment in severe sepsis and septic shock and the influence of dose and duration are examined and analysis of this subgroup suggests a beneficial drug effect on short-term mortality. Expand
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