Survivin gene promoter -31 G/C polymorphism is associated with Wilms tumor susceptibility in Serbian children.

@article{RadojevicSkodric2012SurvivinGP,
  title={Survivin gene promoter -31 G/C polymorphism is associated with Wilms tumor susceptibility in Serbian children.},
  author={Sanja Radojevic-Skodric and Gordana M Basta-Jovanovic and Dimitrije Bra{\vs}anac and Nadja Nikolic and Ljiljana Bogdanovi{\'c} and Biljana Mili{\vc}i{\'c} and Jelena Milasin},
  journal={Journal of pediatric hematology/oncology},
  year={2012},
  volume={34 8},
  pages={
          e310-4
        }
}
Survivin, an apoptotic inhibitor, is overexpressed in various types of cancer. Mechanisms of survivin upregulation are still poorly understood, but single nucleotide polymorphisms in the survivin gene promoter have been shown to modulate survivin expression and consequently the risk for some types of cancer. The aim of the present study was to investigate whether survivin promoter -31 G/C and -241 C/T polymorphisms could represent susceptibility factors for Wilms tumor (WT) development in… CONTINUE READING
1
Twitter Mention

Citations

Publications citing this paper.
SHOWING 1-10 OF 11 CITATIONS

Association of Survivin Polymorphisms with Tumor Susceptibility: A Meta-Analysis

  • PloS one
  • 2013
VIEW 6 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

RECK Gene Polymorphism is Associated with Susceptibility and Prognosis of Wilms’ Tumor in Chinese Children

  • Medical science monitor : international medical journal of experimental and clinical research
  • 2015