Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity.

@article{Beardmore2004SurvivinDI,
  title={Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity.},
  author={Victoria A. Beardmore and Leena J. Ahonen and Gary J Gorbsky and Marko Johannes Kallio},
  journal={Journal of cell science},
  year={2004},
  volume={117 Pt 18},
  pages={4033-42}
}
The inhibitor of apoptosis protein survivin is implicated in two key biological events: in the control of cell proliferation and in the regulation of cell lifespan. Although the details of mitotic roles of survivin are unclear, the protein appears to modulate microtubule function and might participate in regulating the spindle checkpoint. Survivin… CONTINUE READING