Survival of structure and function in postmortem rat and human retinas: rhodopsin regeneration, cGMP and the ERG.

@article{Huang1990SurvivalOS,
  title={Survival of structure and function in postmortem rat and human retinas: rhodopsin regeneration, cGMP and the ERG.},
  author={Jun C. Huang and Mary J. Voaden and John Marshall},
  journal={Current eye research},
  year={1990},
  volume={9 2},
  pages={151-62}
}
Procedures for regenerating visual pigment and restoring phototransduction have been established with freshly isolated, bleached rat retinas. Phosphatidyl choline liposomes containing a 500 microM mixture of retinal isomers, including the 9-cis and 11-cis forms, were employed and the results compared with dark-adapted retinas, incubated similarly but without retinal. The following were recovered in a 60 min incubation, rhodopsin (plus isorhodopsin) to 91% of the original rhodopsin concentration… CONTINUE READING

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