Survival of purified rat photoreceptors in vitro is stimulated directly by fibroblast growth factor-2.

@article{Fontaine1998SurvivalOP,
  title={Survival of purified rat photoreceptors in vitro is stimulated directly by fibroblast growth factor-2.},
  author={Valerie Fontaine and Norbert Kinkl and Jos{\'e} Alain Sahel and Henri Dreyfus and David W. Hicks},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1998},
  volume={18 23},
  pages={9662-72}
}
Basic fibroblast growth factor (FGF-2) influences the differentiation and survival of retinal photoreceptors in vivo and in vitro, but it is not known whether it acts directly on photoreceptor FGF receptors or indirectly through activation of surrounding cells. To clarify the effects of FGF-2 on photoreceptor survival, we developed a purified photoreceptor culture system. The outer nuclear layers of postnatal day 5-15 rat retinas were isolated by vibratome sectioning, and the photoreceptor… CONTINUE READING

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