Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States.

@article{Grossman2010SurvivalOP,
  title={Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States.},
  author={Stuart A. Grossman and Jian L. Campian and Steven Piantadosi and Serena Desideri and Louis B Nabors and Myrna R Rosenfeld and Joy D. Fisher},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2010},
  volume={16 8},
  pages={
          2443-9
        }
}
PURPOSE Novel agents are currently combined with radiation and temozolomide (RT + TMZ) in newly diagnosed glioblastoma using overall survival as the primary end point. Results of these phase II studies are typically compared with the phase III European Organization for Research and Treatment of Cancer (EORTC) survival data that resulted in RT + TMZ becoming standard therapy. EXPERIMENTAL DESIGN The New Approaches to Brain Tumor Therapy (NABTT) Consortium assigned 365 patients with… CONTINUE READING

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