Survival of human epidermal keratinocytes after short-duration high temperature: synthesis of HSP70 and IL-8.

@article{Bowman1997SurvivalOH,
  title={Survival of human epidermal keratinocytes after short-duration high temperature: synthesis of HSP70 and IL-8.},
  author={Phillip D. Bowman and Steven To Schuschereba and David Lawlor and G R Gilligan and Jon{\'a}s Mata and D R DeBaere},
  journal={The American journal of physiology},
  year={1997},
  volume={272 6 Pt 1},
  pages={C1988-94}
}
Thermal injury by short pulses (1-30 s) of relatively high temperature (50-68 degrees C) was investigated in normal human epidermal keratinocytes (NHEK). NHEK were cultured on plastic cover-slips and dipped in medium held at various temperatures. Survival assessed by methylthiazol tetrazolium reduction assay at 6 days postheating demonstrated an inverse time-temperature relationship that indicated that most cells could survive after a 1-s, 60 degrees C exposure or a 30-s, 55 degrees C exposure… CONTINUE READING

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