Survival of classic cholera in Bangladesh

  title={Survival of classic cholera in Bangladesh},
  author={A. K. Siddique and A. Baqui and Abu Eusof and Khaleda Haider and M. Anowar Hossain and Ibrahim Bashir and Kamruz Zaman},
  journal={The Lancet},
During the present cholera pandemic the El Tor biotype of Vibrio cholerae has completely displaced the classic biotype, except in Bangladesh. We studied the distribution of these two biotypes in twenty-four rural districts during epidemics in 1988-89; there was clustering of the classic biotype in the southern region and of the El Tor biotype in all other regions. These findings suggest that the southern coastal region is now (and may always have been) the habitat of classic cholera. The… Expand
Emergence of a new epidemic strain of Vibrio cholerae in Bangladesh. An epidemiological study.
Environmental changes occurring in the Bay of Bengal may have resulted in the emergence of the new epidemic strain of V. cholerae non-O1 (designated as O139 Bengal) in Bangladesh. Expand
Cholera outbreaks in the El Tor biotype era and the impact of the new El Tor variants.
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Cholera outbreaks in the classical biotype era.
Cholera in Bangladesh has recorded a unique history of co-existence of Classical and El Tor biotypes of V. cholerae O1 as epidemic and endemic strain, which has provided great opportunity to improve the understanding of the disease itself and answer some important questions. Expand
Cholera toxin and diarrhoea
Classic cholera was thought to have disappeared and been replaced by the El Tor biotype; however it reappeared as the predominant epidemic strain in 1982 and there was clustering of the classic biotype in the southern region of Bangladeh. Expand
New Variants of Vibrio cholerae O1 Biotype El Tor with Attributes of the Classical Biotype from Hospitalized Patients with Acute Diarrhea in Bangladesh
There are possible naturally occurring genetic hybrids between the classical and El Tor biotypes that can cause cholera and thus provide new insight into the epidemiology of cholERA in Bangladesh. Expand
Vibrio cholerae O139: How great is the threat of a pandemic?
The study suggests that the O139 strain may become endemic in the coastal ecosystem, and the threat of a pandemic, therefore, may not be as large as it first seemed. Expand
Cholera between 1991 and 1997 in Mexico Was Associated with Infection by Classical, El Tor, and El Tor Variants of Vibrio cholerae
The distinct regional fingerprints for ET in Mexico and Peru and their divergence from ET in Asia and Africa, as confirmed by subclustering patterns in a pulsed-field gel electrophoresis (NotI)-based dendrogram, suggest that the Mexico epidemic in 1991 may have been a local event and not an extension of the epidemics occurring in Asia & South America. Expand
Multidrug resistant Vibrio cholerae O 1 and detection of ctx gene from clinical and environmental specimens in Kathmandu valley
Background: Cholera, an infectious disease caused by Vi rio cholerae, is a major public health problem particularly burden in some of the developing countries including N epal. Although the 20 recentExpand
Asiatic Cholera: Mole Hills and Mountains
The disease cholera has persisted in Asia since time immemorial. Almost all the pandemic phases of cholera had its origin from the Indian subcontinent. Historically, waves of cholera have wiped manyExpand
Evolution of new variants of Vibrio cholerae O1.
Recent advances in the understanding of the epidemiology and evolution of the atypical El Tor strains are described. Expand


The mechanism by which a new biotype of V. cholerae 01 achieves such a crucial biological advantage to displace the existing strains may be a key point in control of the global spread of cholera. Expand
Some observations on the cholera (E1 Tor) epidemic in 1961-62.
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The El Tor epidemic did not differ clinically or epidemiologically from other cholera outbreaks observed during the past decade, and attacked poor, under-nourished people living under insanitary conditions. Expand
Endemic cholera in rural Bangladesh, 1966-1980.
While little progress has been made in understanding the mode of transmission of v. cholerae 01, and in identifying practices for prevention, fluid therapy in this area has decreased the case fatality rate significantly and provides guidance for similar programs elsewhere. Expand
Occurrence of Vibrio cholerae serotype O1 in Maryland and Louisiana estuaries
The occurrence of V. cholerae O1 in the aquatic environment in the absence of human disease suggests that this organism survives and multiples in the natural environment. Expand
Ecology, serology, and enterotoxin production of Vibrio cholerae in Chesapeake Bay
It is concluded from the data assembled to date, that V. cholerae is an autochthonous estuarine bacterial species resident in Chesapeake Bay. Expand
Seroepidemiologic studies during a simultaneous epidemic of infection with El Tor Ogawa and classical Inaba Vibrio cholerae.
The simultaneous appearance of both El Tor Ogawa and classical Inaba cholera in Chittagong, East Pakistan, in 1968 provided an opportunity to study cholERA caused by both biotypes in the same community and environment in families of choleria patients. Expand
Effects of temperature and salinity on Vibrio cholerae growth
The results of this study further support the status of V. cholerae as an estuarine bacterium and demonstrate that Na+ was required for growth. Expand