Aberrant DNMT3B7 Expression Correlates to Age, Race, and Hormone Receptor Status in Breast Cancer Patients
- Christian C.S. Mullin, Jennifer J. Busser, Anna M. Ciampanelli, Stacey L. Raimondi
- 2016
Survival of HER2-Positive Breast Cancer Cells: Receptor Signaling to Apoptotic Control Centers.
- Published 2013 in Genes & cancer
Abstract
HER2 is overexpressed in a subset of breast cancers and controls an oncogenic signaling network that inhibits tumor cell death through the specific biochemical regulation of apoptotic pathways. In particular, the mitochondrial pathway for apoptosis is important for death induced by inhibitors of HER2. This review focuses on the connections between this… (More)