Survival in ampullary cancer: potential role of different KRAS mutations.

@article{Valsangkar2015SurvivalIA,
  title={Survival in ampullary cancer: potential role of different KRAS mutations.},
  author={Nakul P. Valsangkar and Thun Ingkakul and Camilo Correa-Gallego and Mari Mino-Kenudson and Ricard Masia and Keith D. Lillemoe and Carlos F Fern{\'a}ndez-del Castillo and Andrew Louis Warshaw and Andrew S Liss and Sarah P. Thayer},
  journal={Surgery},
  year={2015},
  volume={157 2},
  pages={260-8}
}
OBJECTIVE The prognosis of ampullary adenocarcinoma (AA) usually is favorable; however, a subset of AA have poor biology and outcomes similar to pancreatic cancer. Patients in this subset will have early recurrence and death usually within 2 years. To date, there are no genetic markers to identify these patients. This study identifies the high-risk subset of AA and evaluates the mutational status of KRAS in predicting poor outcome. METHODS The tumor registry of an academic center was reviewed… CONTINUE READING
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