Survival implications of opioid use before and after liver transplantation.

  title={Survival implications of opioid use before and after liver transplantation.},
  author={Henry B. Randall and Tarek Alhamad and Mark A. Schnitzler and Zidong Zhang and Sophia Ford-Glanton and David A Axelrod and Dorry L Segev and Bertram L. Kasiske and Gregory P. Hess and Hui Yuan and Rosemary Ouseph and Krista L Lentine},
  journal={Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society},
  volume={23 3},
Implications of prescription opioid use for outcomes after liver transplantation (LT) have not been described. We integrated national transplant registry data with records from a large pharmaceutical claims clearinghouse (2008-2014; n = 29,673). Opioid fills on the waiting list were normalized to morphine equivalents (MEs), and exposure was categorized as follows: > 0-2 ME/day (level 1), > 2-10 ME/day (level 2), > 10-70 ME/day (level 3), and >70 ME/day (level 4). Associations (adjusted hazard… CONTINUE READING
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