Survival following intensive preoperative combined modality therapy with paclitaxel, cisplatin, 5-fluorouracil, and radiation in resectable esophageal carcinoma: a phase I report.

@article{Goldberg2003SurvivalFI,
  title={Survival following intensive preoperative combined modality therapy with paclitaxel, cisplatin, 5-fluorouracil, and radiation in resectable esophageal carcinoma: a phase I report.},
  author={M. Goldberg and J. Farma and C. Lampert and P. Colarusso and L. Coia and H. Frucht and E. Goosenberg and M. Beard and L. Weiner},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={2003},
  volume={126 4},
  pages={
          1168-73
        }
}
PURPOSE To assess the benefits of aggressive chemoradiation therapy followed by surgery in resectable esophageal carcinoma. METHOD Twenty-nine patients with resectable carcinoma were treated with 60 Gy of radiation (2 Gy daily for 6 weeks) and concurrent chemotherapy consisting of continuous infusion of 5-fluorouracil (200-225 mg/m(2)/d), paclitaxel (25, 40, 50, or 60 mg/m(2)) weekly over 1 hour, and cisplatin (25 mg/m(2)) weekly immediately following paclitaxel throughout radiation. Patients… Expand
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  • A. Berger, J. Farma, +5 authors M. Goldberg
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  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 2005
  • 411
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