Survival following intensive preoperative combined modality therapy with paclitaxel, cisplatin, 5-fluorouracil, and radiation in resectable esophageal carcinoma: a phase I report.

@article{Goldberg2003SurvivalFI,
  title={Survival following intensive preoperative combined modality therapy with paclitaxel, cisplatin, 5-fluorouracil, and radiation in resectable esophageal carcinoma: a phase I report.},
  author={M. Goldberg and J. Farma and C. Lampert and P. Colarusso and L. Coia and H. Frucht and E. Goosenberg and M. Beard and L. Weiner},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={2003},
  volume={126 4},
  pages={
          1168-73
        }
}
PURPOSE To assess the benefits of aggressive chemoradiation therapy followed by surgery in resectable esophageal carcinoma. METHOD Twenty-nine patients with resectable carcinoma were treated with 60 Gy of radiation (2 Gy daily for 6 weeks) and concurrent chemotherapy consisting of continuous infusion of 5-fluorouracil (200-225 mg/m(2)/d), paclitaxel (25, 40, 50, or 60 mg/m(2)) weekly over 1 hour, and cisplatin (25 mg/m(2)) weekly immediately following paclitaxel throughout radiation. Patients… Expand
View on PubMed
doi.org
24 Citations
Background Citations
5
Results Citations
1

24 Citations

Citation Type

Citation Type

Weekly cisplatin paclitaxel and continuous infusion fluorouracil in patients with recurrent and/or metastatic head and neck squamous cell carcinoma: a phase II study
  • 11
A phase I trial of definitive chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil (DCF-R) for advanced esophageal carcinoma: Kitasato digestive disease & oncology group trial (KDOG 0501).
  • K. Higuchi, W. Koizumi, +4 authors K. Hayakawa
  • Medicine
  • Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
  • 2008
  • 31
Induction Cisplatin and Paclitaxel Followed by Combination Chemoradiotherapy with 5-Fluorouracil, Cisplatin, and Paclitaxel Before Resection in Localized Esophageal Cancer: A Phase II Report
  • 33
A Phase I study of capecitabine, carboplatin, and paclitaxel with external beam radiation therapy for esophageal carcinoma.
  • 12
Pilot study of preoperative combined modality treatment for locally advanced operable oesophageal carcinoma: toxicities and long-term outcome.
  • 6
A phase I study of UFT/leucovorin, carboplatin, and paclitaxel in combination with external beam radiation therapy for advanced esophageal carcinoma.
  • 1
The role of radiation therapy in the treatment of esophagus cancer
  • 2
Multiple management modalities in esophageal cancer: combined modality management approaches.
  • 79
  • PDF
Salvage esophagectomy following definitive chemoradiotherapy
  • 42
Complete response to neoadjuvant chemoradiotherapy in esophageal carcinoma is associated with significantly improved survival.
  • A. Berger, J. Farma, +5 authors M. Goldberg
  • Medicine
  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 2005
  • 411
...
1
2
3
...

References

SHOWING 1-10 OF 17 REFERENCES
Combined-modality therapy for esophageal cancer: phase I trial of escalating doses of paclitaxel in combination with cisplatin, 5-fluorouracil, and high-dose radiation before esophagectomy.
  • 28
Induction therapy for esophageal cancer with paclitaxel and hyperfractionated radiotherapy: a phase I and II study.
  • 64
Neoadjuvant chemoradiation followed by surgery for resectable esophageal cancer.
  • 8
A comparison of multimodal therapy and surgery for esophageal adenocarcinoma.
  • 1,868
  • PDF
Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus.
  • 1,763
Resectable esophageal carcinoma: local control with neoadjuvant chemotherapy and radiation therapy.
  • 27
Paclitaxel in the treatment of carcinoma of the esophagus.
  • 27
Preoperative chemoradiation followed by transhiatal esophagectomy for carcinoma of the esophagus: final report.
  • 349
Combined modality therapy for esophageal cancer
  • 12
High-dose chemotherapy with autologous stem-cell support for germ cell tumors: a critical review.
  • 20
...
1
2
...