Survival benefit of primary prevention implantable cardioverter-defibrillator therapy after myocardial infarction: does time to implant matter? A meta-analysis using patient-level data from 4 clinical trials.

@article{Hess2013SurvivalBO,
  title={Survival benefit of primary prevention implantable cardioverter-defibrillator therapy after myocardial infarction: does time to implant matter? A meta-analysis using patient-level data from 4 clinical trials.},
  author={Paul L. Hess and Amy E Laird and Rex Edwards and Gust H. Bardy and J. Thomas Bigger and Alfred E. Buxton and Arthur J. Moss and Kerry L. Lee and William Jackson Hall and Richard C. Steinman and P. Dorian and Alfred P. Hallstrom and Riccardo Cappato and Alan H. Kadish and Peter J. Kudenchuk and Daniel B. Mark and Sana M. Al-Khatib and Jonathan P Piccini and Lurdes Y. T. Inoue and Gillian D. Sanders},
  journal={Heart rhythm},
  year={2013},
  volume={10 6},
  pages={828-35}
}
BACKGROUND Whether there is an optimal time to place an implantable cardioverter-defibrillator (ICD) more than 40 days after myocardial infarction (MI) in guideline-eligible patients is unknown. OBJECTIVE To evaluate the effect of time from MI to randomization on mortality, rehospitalizations, and complications. METHODS Individual data on patients enrolled in 9 primary prevention ICD trials were provided. Clinical trials were eligible for the current analysis if they enrolled patients with… CONTINUE READING

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