Survival and late effects in children with Hodgkin's lymphoma treated with MOPP/ABV and low-dose, extended-field irradiation.

@article{Chow2006SurvivalAL,
  title={Survival and late effects in children with Hodgkin's lymphoma treated with MOPP/ABV and low-dose, extended-field irradiation.},
  author={Lionel M. L. Chow and Paul C Nathan and D. C. Hodgson and Derek Jenkin and Sheila Weitzman and Ronald M Grant and David Manson and Adee Bross and John J Doyle and Cyril Danjoux and Mark L. Greenberg},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2006},
  volume={24 36},
  pages={5735-41}
}
PURPOSE Reduced-intensity protocols for pediatric Hodgkin's lymphoma are aimed at preserving excellent relapse-free survival while decreasing the incidence of late effects. PATIENTS AND METHODS We retrospectively reviewed the outcome of 123 children treated consecutively for Hodgkin's lymphoma at a single institution. Patients with stages I-IIIB disease received three cycles of mechlorethamine, vincristine, procarbazine, and prednisone (MOPP)/ doxorubicin, bleomycin, and vinblastine (ABV… CONTINUE READING
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