Survival advantage depends on cecal volume rather than cecal length in a mouse model of cecal ligation and puncture.

Abstract

BACKGROUND Cecal ligation and puncture (CLP) is the most commonly used model to simulate human polymicrobial sepsis. However, the severity of CLP is difficult to be standardized across different laboratories. The aim of the present study was to evaluate the influence of ligated cecal volume and length on mortality in mouse CLP model. METHODS Cecal length… (More)
DOI: 10.1016/j.jss.2016.03.019

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