Survival-Associated Metabolic Genes in Human Papillomavirus-Positive Head and Neck Cancers

  title={Survival-Associated Metabolic Genes in Human Papillomavirus-Positive Head and Neck Cancers},
  author={Martin A. Prusinkiewicz and Steven F. Gameiro and Farhad Ghasemi and Mackenzie J. Dodge and Peter Yu Fan Zeng and Hanna Maekebay and John W. Barrett and Anthony Charles Nichols and Joe S. Mymryk},
Human papillomavirus (HPV) causes an increasing number of head and neck squamous cell carcinomas (HNSCCs). Altered metabolism contributes to patient prognosis, but the impact of HPV status on HNSCC metabolism remains relatively uncharacterized. We hypothesize that metabolism-related gene expression differences unique to HPV-positive HNSCC influences patient survival. The Cancer Genome Atlas RNA-seq data from primary HNSCC patient samples were categorized as 73 HPV-positive, 442 HPV-negative… 

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