Survival, migration and neuronal differentiation of human fetal striatal and cortical neural stem cells grafted in stroke-damaged rat striatum.

@article{Darsalia2007SurvivalMA,
  title={Survival, migration and neuronal differentiation of human fetal striatal and cortical neural stem cells grafted in stroke-damaged rat striatum.},
  author={Vladimer Darsalia and Th{\'e}rese Kallur and Zaal Kokaia},
  journal={The European journal of neuroscience},
  year={2007},
  volume={26 3},
  pages={
          605-14
        }
}
Stroke is a neurodegenerative disorder and the leading cause of disability in adult humans. Treatments to support efficient recovery in stroke patients are lacking. Several studies have demonstrated the ability of grafted neural stem cells (NSCs) to partly improve impaired neurological functions in stroke-subjected animals. Recently, we reported that NSCs from human fetal striatum and cortex exhibit region-specific differentiation in vitro, but survive, migrate and form neurons to a similar… CONTINUE READING
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