Survival, Exercise Capacity, and Left Ventricular Remodeling in a Rat Model of Chronic Mitral Regurgitation: Serial Echocardiography and Pressure-Volume Analysis

Abstract

BACKGROUND AND OBJECTIVES The aims of this study were to establish a reliable model of chronic mitral regurgitation (MR) in rats and verify the pathophysiological features of this model by evaluating cardiac function using serial echocardiography and a pressure-volume analysis. MATERIALS AND METHODS MR was created in 37 Sprague-Dawley rats by making a… (More)
DOI: 10.4070/kcj.2011.41.10.603

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