Surveillance of active human cytomegalovirus infection in hematopoietic stem cell transplantation (HLA sibling identical donor): search for optimal cutoff value by real-time PCR

@inproceedings{Peres2010SurveillanceOA,
  title={Surveillance of active human cytomegalovirus infection in hematopoietic stem cell transplantation (HLA sibling identical donor): search for optimal cutoff value by real-time PCR},
  author={Renata MB Peres and Cl{\'a}udia RC Costa and Paula Durante Andrade and Sandra HA Bonon and Dulcineia Martins de Albuquerque and Cristiane H Y de Oliveira and Afonso Celso Vigorito and Francisco JP Aranha and C{\'a}rmino Ant{\^o}nio de Souza and Sandra CB Costa},
  booktitle={BMC infectious diseases},
  year={2010}
}
BACKGROUND Human cytomegalovirus (CMV) infection still causes significant morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). Therefore, it is extremely important to diagnosis and monitor active CMV infection in HSCT patients, defining the CMV DNA levels of virus replication that warrant intervention with antiviral agents in order to accurately prevent CMV disease and further related complications. METHODS During the first 150 days after allogeneic HSTC… CONTINUE READING

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Eleven ( 40.7% ) of these 27 patients had acute GVHD , 18 ( 66.7% ) had opportunistic infection , 5 ( 18.5% ) had chronic rejection and 11 ( 40.7% ) died - one died of CMV disease associated with GVHD and bacterial infection .
Eleven ( 40.7% ) of these 27 patients had acute GVHD , 18 ( 66.7% ) had opportunistic infection , 5 ( 18.5% ) had chronic rejection and 11 ( 40.7% ) died - one died of CMV disease associated with GVHD and bacterial infection .
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