Surveillance in the routine management of ulcerative colitis: the predictive value of low-grade dysplasia.

@article{Woolrich1992SurveillanceIT,
  title={Surveillance in the routine management of ulcerative colitis: the predictive value of low-grade dysplasia.},
  author={A J Woolrich and M Dasilva and Burton I. Korelitz},
  journal={Gastroenterology},
  year={1992},
  volume={103 2},
  pages={431-8}
}
Biopsies obtained at colonoscopy from 121 patients with ulcerative colitis (UC) for greater than 7 years were reviewed. Dysplasia or neoplasia was found in 27 patients (22%) after a mean of 16 years; 22 (18%) had dysplasia (all low grade), 2 had polyps, and 3 had carcinoma without prior dysplasia. Seven had dysplasia (or neoplasia) on the next examination, and another 4 after multiple negative examinations. Dysplasia preceded carcinoma in 4 (18%) of the 22 patients, and carcinoma occurred in 7… CONTINUE READING

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