Surveillance and modification of immunosuppression minimizes BK virus nephropathy.

  title={Surveillance and modification of immunosuppression minimizes BK virus nephropathy.},
  author={W. M. Bennett and Leslie E Meyer and Jennifer Ridenour and Thomas D Batiuk},
  journal={American journal of nephrology},
  volume={32 1},
BACKGROUND/AIMS Infection of a transplanted kidney with the polyomavirus, BK, is associated with poor allograft survival. METHODS In an attempt to prevent this transplant complication, we studied 144 consecutive transplant recipients for the presence of BK infection with plasma and urine PCR testing at 1, 2, 3, 6 and 12 months. Viruria alone was followed by serial studies. If plasma PCR became positive at >2.6 log copies, mycophenolate was reduced until there was no detectable plasma viral… CONTINUE READING

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