Surugapyrroles A and B, two new N-hydroxypyrroles, as DPPH radical-scavengers from Streptomyces sp. USF-6280 strain.

Abstract

Two new N-hydroxypyrroles, surugapyrroles A and B, were isolated as DPPH radical-scavengers from a culture broth of Streptomyces sp. USF-6280 strain. The structures of the two compounds were elucidated by spectroscopic evidences and derivatization. Their DPPH (2,2-diphenyl-1-picrylhydrazyl) radical-scavenging activity was as high as that of butylhydroxytoluene (BHT): surugapyrrole A, ED(50) 50.3 microM; surugapyrrole B, ED(50) 75.8 microM.

Cite this paper

@article{Sugiyama2009SurugapyrrolesAA, title={Surugapyrroles A and B, two new N-hydroxypyrroles, as DPPH radical-scavengers from Streptomyces sp. USF-6280 strain.}, author={Yasumasa Sugiyama and Kei Watanabe and Akira Hirota}, journal={Bioscience, biotechnology, and biochemistry}, year={2009}, volume={73 1}, pages={230-2} }